The development of biomarkers will be performed with the combination of structural, molecular and functional information obtained by imaging techniques, together with the molecular data of the mechanisms of the diseases obtained by omic techniques. This approach opens up new perspectives in the study of these complex diseases. The final aim of these biomarkers is their clinical application for diagnosis, monitoring and evaluation of response to treatment in patients with diseases that affect the pulmonary circulation.
Our group at CIC biomaGUNE is mainly interested in the study of pulmonary vascular diseases using different approaches. Pulmonary vascular function is directly or indirectly compromised in various diseases, such as Pulmonary Hypertension. Pulmonary vascular dysfunction can lead to failure of the right ventricle, which dramatically worsens the prognosis of patients. The study of the pulmonary circulation and the right ventricle (RV) is a field of growing interest and its relevance is increasingly emphasized. Our research group is devoted to the discovery of biomarkers with diagnostic and prognostic values for these diseases.