by C Aragon, Caio, M Palomo, Jose, Filice, Marco and Mateo, Cesar
Abstract:
The aldol reactions catalyzed by aldolases are an important tool in the synthesis of different products or building blocks. However, despite its advantages, aldolases, as enzymes, have some troubles as their low activity against synthetic substrates or the low stability, doing difficult their application. There are different tools to improve the properties of this enzyme such as directed mutagenesis, directed evolution or the immobilization methods. The immobilization not only is able to improve the properties of the enzymes but also permits the reuse of the catalysts. This review is focused on the immobilization of different aldolases using different methodologies.
Reference:
Immobilization of Aldolase for C-C Bond Formation (C Aragon, Caio, M Palomo, Jose, Filice, Marco and Mateo, Cesar), In Current Organic Chemistry, volume 20, 2016.
Bibtex Entry:
@article{CAragon:2016cl,
author = {C Aragon, Caio and M Palomo, Jose and Filice, Marco and Mateo, Cesar},
title = {{Immobilization of Aldolase for C-C Bond Formation}},
journal = {Current Organic Chemistry},
year = {2016},
volume = {20},
number = {11},
pages = {1243--1251},
month = mar,
annote = {IF 1.949. JCR Chemistry Organic. 33/59  Q2},
doi = {10.2174/1385272819666150831202640},
language = {English},
rating = {0},
date-added = {2016-08-16T15:59:53GMT},
date-modified = {2018-03-16T13:14:13GMT},
abstract = {The aldol reactions catalyzed by aldolases are an important tool in the synthesis of different products or building blocks. However, despite its advantages, aldolases, as enzymes, have some troubles as their low activity against synthetic substrates or the low stability, doing difficult their application. There are different tools to improve the properties of this enzyme such as directed mutagenesis, directed evolution or the immobilization methods. The immobilization not only is able to improve the properties of the enzymes but also permits the reuse of the catalysts. This review is focused on the immobilization of different aldolases using different methodologies.},
url = {http://www.eurekaselect.com/openurl/content.php?genre=article&issn=1385-2728&volume=20&issue=11&spage=1243},
local-url = {file://localhost/Users/jruizcabello/Documents/JRC/biblio/Papers-folder/Library.papers3/Files/E0/E029DF64-5451-4934-9811-B1768BA3FD04.pdf},
file = {{E029DF64-5451-4934-9811-B1768BA3FD04.pdf:/Users/jruizcabello/Documents/JRC/biblio/Papers-folder/Library.papers3/Files/E0/E029DF64-5451-4934-9811-B1768BA3FD04.pdf:application/pdf}},
uri = {url{papers3://publication/doi/10.2174/1385272819666150831202640}}
}