by Qiu, Bensheng, Xie, Daohai, Walczak, Piotr, Li, Xubin, Ruiz-Cabello, Jesus, Minoshima, Satoshi, Bulte, Jeff W M and Yang, Xiaoming
Abstract:
The purpose of this study was to develop an instant MR cell labeling technique, called magnetosonoporation. First, a magnetosonoporation apparatus was successfully established for MR labeling of stem cells. Then, the safety of this new cell labeling approach was confirmed by evaluation of cell viability, proliferation, and differentiation of magnetosonoporation-labeled and unlabeled C17.2 neural stem cells. Subsequently, the feasibility of using in vivo MRI to detect magnetosonoporation/Feridex-labeled stem cells was validated in living animals and confirmed by histologic correlation. The magnetosonoporation technique is expected to be convenient, efficient, and safe for future clinical application of MRI-guided cell therapies.
Reference:
Magnetosonoporation: instant magnetic labeling of stem cells. (Qiu, Bensheng, Xie, Daohai, Walczak, Piotr, Li, Xubin, Ruiz-Cabello, Jesus, Minoshima, Satoshi, Bulte, Jeff W M and Yang, Xiaoming), In Magn Reson Med, Wiley Subscription Services, Inc., A Wiley Company, volume 63, 2010.
Bibtex Entry:
@article{Qiu:2010fzd,
author = {Qiu, Bensheng and Xie, Daohai and Walczak, Piotr and Li, Xubin and Ruiz-Cabello, Jesus and Minoshima, Satoshi and Bulte, Jeff W M and Yang, Xiaoming},
title = {{Magnetosonoporation: instant magnetic labeling of stem cells.}},
journal = {Magn Reson Med},
year = {2010},
volume = {63},
number = {6},
pages = {1437--1441},
month = jun,
publisher = {Wiley Subscription Services, Inc., A Wiley Company},
affiliation = {Image-Guided Bio-Molecular Interventions Section, Department of Radiology, University of Washington School of Medicine, Seattle, Washington 98195, USA. bqiu@u.washington.edu},
doi = {10.1002/mrm.22348},
pmid = {20512844},
language = {English},
rating = {0},
date-added = {2018-03-16T12:57:12GMT},
date-modified = {2018-04-04T07:59:10GMT},
abstract = {The purpose of this study was to develop an instant MR cell labeling technique, called magnetosonoporation. First, a magnetosonoporation apparatus was successfully established for MR labeling of stem cells. Then, the safety of this new cell labeling approach was confirmed by evaluation of cell viability, proliferation, and differentiation of magnetosonoporation-labeled and unlabeled C17.2 neural stem cells. Subsequently, the feasibility of using in vivo MRI to detect magnetosonoporation/Feridex-labeled stem cells was validated in living animals and confirmed by histologic correlation. The magnetosonoporation technique is expected to be convenient, efficient, and safe for future clinical application of MRI-guided cell therapies.},
url = {http://doi.wiley.com/10.1002/mrm.22348},
uri = {url{papers3://publication/doi/10.1002/mrm.22348}}
}